A prominent theme in chemistry and biology is to understand the structures and functions of nucleic acids (NAs), and to engineer them for a wide range of applications. Factors impeding the structural analysis of artificial NA nanoarchitectures involves high conformational plasticity of these structures, and crystallization difficulties of NA molecules. Though advances in nanotechnology have enabled the construction of synthetic nucleic acid-based nanoarchitectures with ever-increasing complexity for various applications, high-resolution structures are lacking due to the difficulty of obtaining good diffracting crystals. Here you can see the atomic configuration of an RNA nanostructure based on homooligomerizable tiles from an RNA single-strand for X-ray determination. This structure correspond to a small nanocage formed by two symmetrical single-stranded RNA molecules (PDB code: 7JRS)
#molecularart ... #immolecular ... #RNA ... #nucleicacid ... #Xray ... #selfassembly ... #nanocage ... Rendered with @proteinimaging and finished with @corelphotopaint
#molecularart ... #immolecular ... #RNA ... #nucleicacid ... #Xray ... #selfassembly ... #nanocage ... Rendered with @proteinimaging and finished with @corelphotopaint
